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Regenerative medicine

Regenerative medicine is a collective term for medical technology designed to restore functions lost by organs and tissues that have suffered impairment or dysfunction. In the field of regenerative medicine, the relative merits of ideas are of course important; but in fact, the quality of intricate technical processes and tools that can achieve the necessary cell culture also has a major part to play. A wide range of regenerative medicine technologies are currently being developed and clinical applications are being explored on a global scale, and in Japan in particular, clinical research on corneal transplantation and heart failure treatment employing autologous cell sheets is being conducted. Although the efficacy of treatments with autologous cell sheets has not been fully established and further verification is required, some patients have responded well to such treatments. International patients can participate in this clinical research at their request.

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Autologous cell sheets

What is an autologous cell sheet?

An autologous cell sheet is a sheet-shaped culture of cells that are collected from a patient and grown in special equipment. Usually, cells are grown into a sheet-like shape on a culture plate, but become separated when they are peeled off. However, when special equipment is used, the sheet-like shape can be maintained, and regeneration of damaged tissues and organs is promoted by applying such a sheet. Layered sheets are prepared according to the size of the tissues and organs. Because this sheet is made of the patient’s own cells, no rejection occurs, and research is in progress to apply it to other organs such as the cornea, cardiac muscle, esophagus, periodontal tissues, and cartilage.

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